Medically referred to as cephalalgia, headaches have a mess of causes, like sleep deprivation, dehydration, stress, eyestrain, sinus pain, and muscle tension. Where there’s a disorder or pain somewhere within the body, nociceptors, which are pain-sensitive receptors at the ends of nerve fibers, are activated. The nociceptors send a sign to the brain, which the brain interprets as pain. A headache results. the world of the top where the pain is felt depends on the situation of the activated nociceptors. When the brain is alerted to pain, it also produces variety of chemicals, including serotonin, that act to scale back pain. However, the discharge of those chemicals can cause a swelling of blood vessels within the brain, making the blood vessels tender. The swollen vessels then irritate the nerve fibers that surround them within the head. These nerve fibers send messages to the trigeminal system, which is a neighborhood of the brain handling pain within the face and head. this will cause the headache to worsen. Medication to alleviate the consequences of a headache works best if taken early. Once the pathways for the pain signals, transmitted by the nerves, are fully activated, it’s harder to stop the signals and thus reduce the headache.